How To Use CREATINE To Build Muscle Loading, Timing & Hair Loss (Science Explained)

This entry is part [part not set] of 48 in the series Science Explained Series by Jeff Nippard

Introduction

The supplement industry often faces criticism due to false marketing and overpriced products. However, creatine is a supplement that has consistently proven its efficacy and affordability. With over 700 human studies investigating its safety and effectiveness, creatine is the most well-researched sports supplement. This article will explore the benefits of creatine supplementation, how it works, and the potential concerns associated with its use.

Understanding Creatine

  • Creatine is a small tripeptide made up of three amino acids linked together.
  • Our bodies can produce it naturally, and it’s found in uncooked meats.
  • Supplementation is necessary to achieve creatine’s performance and physique-enhancing effects, as natural sources provide insufficient amounts.

How Creatine Works

  • Creatine helps produce ATP (adenosine triphosphate), the main energy currency used in the body.
  • It is particularly useful for fast, high-intensity activities that require a quick source of ATP.
  • Supplementation increases creatine stores by 20-40%, leading to better performance and muscle growth.

Optimizing Creatine Supplementation

  • The fastest way to reach saturation is through creatine loading, followed by a maintenance phase.
  • Take 20-25 grams per day for a week, then reduce to 5 grams per day to maintain saturation.
  • Alternatively, start with a 5 grams maintenance dose without loading, but it may take up to a month to reach saturation and see results.

Benefits of Creatine

  • Increases maximal strength and power by 5-15%.
  • Improves workout performance and training volume, leading to more muscle growth over time.
  • Causes intramuscular water retention, which could further increase muscle growth through cellular swelling mechanisms.

Potential Concerns

  • Non-responders: 20-30% of people may not respond to creatine supplementation, particularly those with high meat consumption and older trainees.
  • No need to cycle off creatine, as the body does not develop a tolerance to its effects.
  • Combining creatine and caffeine is not a concern, as most studies show a synergistic effect.
  • Male pattern baldness: Creatine may contribute to hair loss in men with a genetic predisposition or family history. Consider stacking with finasteride to reduce DHT conversion.

Conclusion

Creatine supplementation offers numerous benefits for athletic performance and muscle growth. Its affordability and extensive scientific backing make it a valuable addition to any fitness regimen. While potential concerns exist, the benefits of creatine far outweigh the costs, making it a supplement that truly lives up to the hype.

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